Tumor Suppressor Genes (TSG)

Tumor Suppressor Genes (TSG) –A class of genes with various functions but with one common feature: to prevent a cell from development into a neoplastic cancer cell. Silencing of tumor suppressor genes by DNA methylation is an early and frequent epigenetic event in tumorigenesis.

Showing 1–9 of 73 results

EpiMelt APC assay

Homo sapiens adenomatous polyposis coli (APC), NM_001127511

DNA Methylation Assay Kit for APC, based on MS-HRM. Includes controls.

 

EpiMelt MLH1 assay

Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), NM_000249

DNA Methylation Assay Kit for MLH1 based on MS-HRM. Includes controls

EpiMelt MGMT assay

Homo sapiens O-6-methylguanine-DNA methyltransferase (MGMT), NM_002412

DNA Methylation Assay Kit for MGMT based on MS-HRM. Includes controls.

EpiMelt BRCA1 assay

Homo sapiens breast cancer 1, early onset (BRCA1), NM_007299

DNA Methylation Assay Kit for BRCA1, based on MS-HRM. Includes controls

EpiMelt BRCA2 assay

Homo sapiens breast cancer 2, early onset (BRCA2), NM_000059

DNA Methylation Assay Kit for BRCA2, based on MS-HRM. Includes controls

 

EpiMelt RASSF1A assay

Homo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), NM_170714

DNA Methylation Assay Kit for RASSF1A, based on MS-HRM. Includes controls

 

EpiMelt CDH1 assay

Homo sapiens cadherin 1, type 1, E-cadherin (epithelial) (CDH1), NM_004360

DNA Methylation Assay Kit for CDH1, based on MS-HRM. Includes controls

 

EpiMelt CDH13 assay

Homo sapiens cadherin 13, H-cadherin (heart) (CDH13), NM_001220492

DNA Methylation Assay Kit for CDH13, based on MS-HRM. Includes controls