TGFß Signaling Pathway

TGF-b Signaling Pathway – This pathway primally regulates cell growth and dedifferentiation. Deregulation of this pathway was associated with various cancer types. Crosstalk between TGF-b signaling and the epigenome may influence the transcriptional regulation during embryonic development, and epigenetic aberrations affecting TGF-b signaling promote progression of various diseases as cancer.

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