Welcome to MethylDetect

We make ready to use DNA Methylation Assays

Welcome to MethylDetect

We make ready to use DNA Methylation Assays

We offer ready-to-use assays, customer tailored services and more. Read about our services here:

Ready to use DNA Methylation Assays

 Cost-effective

Fast and robust

User friendly

Ready to use DNA Methylation Assays

Cost-effective
Fast and robust
User friendly

Customer Tailored Services

 We design assay to your gene of interest and send it to you.
We test your samples at our facilities.

Customer Tailored Services

We design assay to your gene of interest and send it to you.
We test your samples at our facilities.

MS-HRM Technology

 We determine methylation status of your favourite gene with MS-HRM Technology.

 

MS-HRM Technology

We determine methylation status of your favourite gene with MS-HRM Technology.

 

MethylDetect introduces:

DNA Methylation is one of the most widely studied epigenetic mechanisms of gene expression regulation.

Aberrant methylation of increasing number of genes is being shown to contribute to the majority of diseases such as cancer, cardiovascular disorders, aging, obesity, allergy, diabetes, depression, Alzheimer’s, Parkinson’s or schizophrenia.

 

 

Read more

Solid research evidence already shows that DNA methylation-based biomarkers can be utilized at all stages of clinical disease management including:

  • Disease risk assessment
  • Early detection
  • Personalization of treatment
  • Monitoring of chronic disorders and recurrence

The technology is already in use for detection of DNA methylation biomarkers in fields like forensics, and for investigating challenging DNA materiel sources as liquid biopsies and FFPE tissues.

MethylDetect offers ready-to-use kits for detection of aberrant gene methylation. The kits are based on the MS-HRM (Methylation Sensitive High Resolution Melting) technology and can be used with standard laboratory equipment. Additionally, our new controls system shipped with each kit, provides state-of-the-art experimental reliability.

methyldetect pipettes

Assay Specific Control System

Designed to ensure optimal measurement of methylation. Applicable to the majority of methylation screening technologies.
Generation of standard curves for technologies such as q-MSP or MethyLight.

 

DNA Methylation detection using the EpiMelt kit

 

 

1. ADD

The MethylDetect kit components and the bisulfite modified biological samples to the PCR reagents

 

 

1. AMPLIFY

Use a standard laboratory Real Time-PCR system to PCR amplify the target

 

 

3. DETECT

Assess the methylation status of the sequence of interest with a High-Resolution Melting Module

 

 

Epigenetics and Epigenomics in Health and Disease PMF Brussels 2020 https://t.co/npmSI7nHa4
Just published a method for automated analysis of #methylation #epigenetics data #PCR #diagnostics

Methylation levels assessment with Methylation-Sensitive High-Resolution Melting (MS-HRM) https://t.co/LyM5ps4llA

Get in touch

Please contact us if you have questions about our company, our products, or general enquiries.
Please use the form below.

 

Get in touch

Please contact us if you have questions about our company, our products, or general enquiries.
Please use the form below.

 

Epigenetics and Epigenomics in Health and Disease PMF Brussels 2020 https://t.co/npmSI7nHa4
Just published a method for automated analysis of #methylation #epigenetics data #PCR #diagnostics

Methylation levels assessment with Methylation-Sensitive High-Resolution Melting (MS-HRM) https://t.co/LyM5ps4llA