Inflammation is a response to infection or cell injury. Uncontrolled inflammatory response can lead to disease and this process is also a significant part of carcinogenesis.
Inflammatory response is closely related to autoimmunity where immune cells begin to attack other cells of the organism. This process is part of the pathology of autoimmune diseases such as lupus or arthritis.
Epigenetic dysregulation directly influences the development of autoimmunity by regulating the immune cell function, as DNA methylation underlying the regulation of T-cell maintenance.