Inflammatory response and autoimmunity

Inflammation is a response to infection or cell injury. Uncontrolled inflammatory response can lead to disease and this process is also a significant part of carcinogenesis.

Inflammatory response is closely related to autoimmunity where immune cells begin to attack other cells of the organism. This process is part of the pathology of autoimmune diseases such as lupus or arthritis.

Epigenetic dysregulation directly influences the development of autoimmunity by regulating the immune cell function, as DNA methylation underlying the regulation of T-cell maintenance.

Showing 1–9 of 93 results

EpiMelt SOD1 test assay

Homo sapiens superoxide dismutase 1 (SOD1), (NM_000454

DNA Methylation Assay Kit for SOD1 based on MS-HRM. Includes controls

EpiMelt NFKB1 test assay

Homo sapiens nuclear factor kappa B subunit 1 (NFKB1), NM_003998

DNA Methylation Assay Kit for NFKB1 based on MS-HRM. Includes controls

EpiMelt TNFRSF1B test assay

Homo sapiens TNF receptor superfamily member 1B (TNFRSF1B), NM_001066

DNA Methylation Assay Kit for TNFRSF1B based on MS-HRM. Includes controls

EpiMelt IL6R test assay

Homo sapiens interleukin 6 receptor (IL6R), NM_001382774

DNA Methylation Assay Kit for IL6R based on MS-HRM. Includes controls

EpiMelt IL4R test assay

Homo sapiens interleukin 4 receptor (IL4R), NM_001257406

DNA Methylation Assay Kit for IL4R based on MS-HRM. Includes controls

EpiMelt HDAC4 test assay

Homo sapiens histone deacetylase 4 (HDAC4), NM_006037

DNA Methylation Assay Kit for HDAC4 based on MS-HRM. Includes controls

EpiMelt CXCR4 test assay

Homo sapiens C-X-C motif chemokine receptor 4 (CXCR4), NM_003467

DNA Methylation Assay Kit for CXCR4 based on MS-HRM. Includes controls

EpiMelt CXCL12 test assay

Homo sapiens C-X-C motif chemokine ligand 12 (CXCL12), NM_199168

DNA Methylation Assay Kit for CXCL12 based on MS-HRM. Includes controls